RNA Details
Disease Name
myocardical ischemia
Tissue
heart
RNA Symbol
mir-377
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
dual-luciferase reporter assay;
Target
VEGF
Pathway
NA
PubMed ID
Title
MicroRNA-377 regulates mesenchymal stem cell-induced angiogenesis in ischemic hearts by targeting VEGF
Year
2014
Function
"Hypoxia-responsive miR-377 directly targets VEGF in mesenchymal stem cells (MSCs), and knockdown of endogenous miR-377 promotes MSC-induced angiogenesis in the infarcted myocardium."